NCT04597762

Effect of Ciclosporin Eyedrops on Sjögren Syndrome

Effect of Ciclosporin Eyedrops on Ocular Symptoms and Optical Quality in Patients With Sjögren Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Hospital Hietzing · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Keratoconjunctivitis sicca, also known as dry eye syndrome, is one of the most common ophthalmological diseases and is treated with tear substitutes to moisten the surface of the eye and, in more severe cases of this disease, with local anti-inflammatory therapy with corticosteroids or ciclosporin A. In patients with rheumatological diseases, such as Sjögren's syndrome, dry eye syndrome of severe extent occurs particularly frequently, which is why topical anti-inflammatory therapy is often necessary in these patients. Aim of this study is to evaluate the treatment of severe dry eye syndrome with topical cyclosporin eyedrops with and without topical corticosteroids at the beginning of the treatment.

Conditions

• Dry Eye Syndromes

Interventions

Type	Name	Description
DRUG	Cyclosporin	Cyclosporin eyedrops
DRUG	Hydrocortisone	Hydrocortisone eyedrops

Timeline

• Start date: 2020-08-31
• Primary completion: 2021-03-30
• Completion: 2021-03-31
• First posted: 2020-10-22
• Last updated: 2021-04-08

Locations

1 site across 1 country: Austria