NCT04589897

Manuka Honey Sinus Rinse Study

A Pilot Study Investigating the Effects of a Manuka Honey Sinus Rinse on Sino-nasal Outcome Test Scores in Cystic Fibrosis Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: Swansea University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A trial investigating the effect of a sinus rinse in people with CF

Detailed description

People with with CF often have bacterial infection in their air ways. There is great interest in the different types of bacteria found within these infections. This clinical trial looks at whether a novel sinus rinse device (that incorporates manuka honey) could help clear infection or reduce the amount and/or types of bacteria found within the upper airway. This study assesses the changes in the Sino-Nasal Outcome Test (SNOT-22) scores along with any changes in quality of life, before and after the use of a sinus rinse device for 30 days. In addition to this, the amount and types of bacteria found in nasal swabs, the sinus rinse solution, and sputum samples, before and after using the sinus rinse device will be investigated. Sputum samples will also be monitored for changes in composition before and after using the sinus rinse.

Conditions

• Cystic Fibrosis
• Infection, Bacterial

Interventions

Type	Name	Description
DEVICE	Manuka honey sinus rinse	Will follow a modified NHS nasal rinse protocol with the addition of manuka honey
DEVICE	Standard sinus rinse	will follow the standard NHS nasal rinse protocol

Timeline

• Start date: 2019-01-07
• Primary completion: 2021-10-31
• Completion: 2021-10-31
• First posted: 2020-10-19
• Last updated: 2022-09-22

Locations

1 site across 1 country: United Kingdom