NCT04564950

Influence of Periodontitis and Coronary Heart Disease on Galectin-3

Influence of Periodontitis and Coronary Heart Disease on Galectin-3 in Serum and Saliva

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 155 (actual)
• Sponsor: University of Messina · Academic / Other
• Sex: All
• Age: 30 Years – 70 Years
• Healthy volunteers: —

Summary

The aim of this study was to analyze the association between serum and salivary Galectin-3 levels in patients with periodontitis. Furthermore, the objective was to determine if the periodontitis influenced serum and salivary Galectin-3 levels

Detailed description

Healthy controls (n=38), patients with CHD (n=39), periodontitis (n=40), and a combination of periodontitis + CHD (n=38) were enrolled in the present study. The analyzed sample undergo a demographical, clinical and periodontal evaluation and serological analyses including Endothelin-1 (ET-1) and for serum and salivary Galectin-3 levels.

Conditions

• Periodontal Diseases

Interventions

Type	Name	Description
OTHER	Observation of serum and salivary Galectin-3 levels	Observation of serum and salivary Galectin-3 levels and correlation with periodontal indices

Timeline

• Start date: 2016-04-01
• Primary completion: 2018-07-30
• Completion: 2018-07-31
• First posted: 2020-09-25
• Last updated: 2020-12-21

Locations

1 site across 1 country: Italy