NCT04553757

Seizure Control as a New Metric in Assessing Efficacy of Tumor Treatment in Patients With Low Grade Glioma

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: M.D. Anderson Cancer Center · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This study investigates how seizures can vary over time with changes in low grade gliomas and its treatments. This study may help doctors find symptoms or triggers of seizures earlier than normal, and ultimately earlier care or treatment for seizures.

Detailed description

PRIMARY OBJECTIVE: I. To evaluate the rate of change of seizure frequency and the status of the tumor at each data collection point. SECONDARY OBJECTIVES: I. To obtain sufficient number of patients' data in order to power the analysis to determine whether a change in seizure frequency correlates with tumor control. II. Evaluate progression free survival and overall survival when compared with seizure control. OUTLINE: Patients complete a seizure assessment survey over 5 minutes at each clinic visit.

Conditions

• Brain Neoplasm
• Low Grade Glioma
• Seizure Disorder

Interventions

Type	Name	Description
OTHER	Survey Administration	Complete survey

Timeline

• Start date: 2020-07-08
• Primary completion: 2025-12-30
• Completion: 2025-12-30
• First posted: 2020-09-17
• Last updated: 2025-10-24

Locations

1 site across 1 country: United States