Trials / Completed
CompletedNCT04542668
The Effect of Exercise on Serum Levels of Collagen and Proteoglycan in Patients With Knee Osteoarthritis
An Open-label, Randomized, Cross-over Study to Investigate the Effect of Weight-bearing vs Non-weight-bearing Exercise and Cardiovascular Stress Without Load on Collagen and Proteoglycan in Serum and Urine in Patients With Osteoarthritis
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (actual)
- Sponsor
- Nordic Bioscience A/S · Industry
- Sex
- All
- Age
- 40 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The aim of EFEX-OA-02 is to explore how running, cycling, exercise simulation and resting acutely influence collagen and proteoglycan homeostasis in OA, as reflected by changes in collagen and proteoglycan levels in urine and serum.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Cycling then running | Ergometer cycling Treadmill running |
| OTHER | Running then cycling | Treadmill running Ergometer cycling |
| OTHER | Inotropy | Adrenaline induced inotropy |
| OTHER | Resting | Subjects must be minimally physically active |
Timeline
- Start date
- 2020-10-08
- Primary completion
- 2021-06-07
- Completion
- 2021-06-07
- First posted
- 2020-09-09
- Last updated
- 2021-06-08
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT04542668. Inclusion in this directory is not an endorsement.