NCT04540328

Non-surgical Peridontal Treatment on Cardiovascular Risk Markers

Effect of Non-surgical Peridontal Treatment on Cardiovascular Risk Markers in Patients With Severe Chronic Periodontitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Kırıkkale University · Academic / Other
• Sex: All
• Age: 30 Years – 54 Years
• Healthy volunteers: Accepted

Summary

The study evaluates the influence of non-surgical mechanical periodontal treatment in patients with severe chronic periodontitis on inflammatory markers related to risk for cardiovascular diseases

Detailed description

A total of 80 non-smokers with systemically healthy, including 40 patients with severe chronic periodontitis and 40 periodontally health subjects were included into the present study. The probing depth, clinical attachment level, plaque index, gingival index and blood samples were collected at baseline and at the 3rd months after treatment and the serum levels of asymmetric dimethylarginine (ADMA), endothelial nitric oxide synthase (eNOS), homocysteine (Hcy), monocyte chemoattractant protein-1 (MCP-1) were determined with enzyme-linked immunosorbent assay (ELISA).

Conditions

• Cardiovascular Risk Markers
• Chronic Periodontitis

Interventions

Type	Name	Description
OTHER	Non-surgical periodontal treatment

Timeline

• Start date: 2015-08-01
• Primary completion: 2016-02-01
• Completion: 2017-08-01
• First posted: 2020-09-07
• Last updated: 2020-09-07