NCT04534426

Topical Arnica and Mucopolysaccharide Polysulfate on Postoperative Pain, Edema and Trismus

Influence of Different Topical Arnica and Mucopolysaccharide Polysulfate on Postoperative Pain, Edema and Trismus After Extraction of Impacted Third Molar

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Abant Izzet Baysal University · Academic / Other
• Sex: All
• Age: 16 Years – 68 Years
• Healthy volunteers: Accepted

Summary

The present study was to evaluate the effect of topical Arnica and MPSP application with respect to visual analogue scale (VAS) scores, maximal interincisal opening (MIO) and edema values after mandibular impacted third molar removal on days 1, 3, 5 and 10 postoperatively. The following null hypotheses of the present research were determined as follows: usage of topical agents would not influence i) VAS scores, ii) MIO values, and iii) edema values on 1st, 3rd, 5th, and 10th days after the mandibular impacted third molar surgery

Conditions

• Impacted Third Molar Tooth

Interventions

Type	Name	Description
DRUG	: Arnica montana	In Arnica group, patients were given an unlabelled tube containing cream to be applicated topically on skin surface of masseteric and submandibular region, 2 cm in length cream for each 8 hours, starting immediately after surgery and continued for 10 days
DRUG	Mucopolysaccharide polysulfate	In Arnica group and MPSP group, patients were given an unlabelled tube containing cream to be applicated topically on skin surface of masseteric and submandibular region, 2 cm in length cream for each 8 hours, starting immediately after surgery and continued for 10 days
OTHER	Control group	In Control group, only standard therapy was performed after surgery

Timeline

• Start date: 2018-12-01
• Primary completion: 2019-12-01
• Completion: 2020-01-30
• First posted: 2020-09-01
• Last updated: 2020-09-01

Locations

1 site across 1 country: Turkey (Türkiye)