Trials / Completed
CompletedNCT04482517
Reproductive Outcomes of Different Sperm Selection Techniques for ICSI Patients With Abnormal Sperm DNA Fragmentation.
Reproductive Outcomes of Different Sperm Selection Techniques; Density Gradient Centrifugation, Testicular Sperm, PICSI, and MACS for ICSI Patients With Abnormal Sperm DNA Fragmentation
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 320 (actual)
- Sponsor
- Ganin Fertility Center · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
Comparing the reproductive outcomes of different sperm selection techniques; Density gradient centrifugation (DGC), Testicular sperm (Testi), Physiological ICSI (PICSI), and Magnetic activated cell sorting (MACS) in abnormal sperm DNA fragmentation (SDF) ICSI patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Density Gradient Centrifugation | Semen processing is done by double layer density gradient method. |
| OTHER | Physiological ICSI | Sperm selection by PICSI dishes depending on hyaluronan binding of sperm head |
| OTHER | Magnetic activated cell sorting | Sperm selection by using Annexin V micro-beads and separation columns |
| OTHER | Testicular sperm | Using testicular sperm retrieved by TESA or TESE |
Timeline
- Start date
- 2017-03-01
- Primary completion
- 2018-12-01
- Completion
- 2018-12-01
- First posted
- 2020-07-22
- Last updated
- 2020-07-22
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT04482517. Inclusion in this directory is not an endorsement.