NCT04477317

Anesthetic Efficacy of %4Alexadricaine Versus %2 Mepicaine-L in Children

Anesthetic Efficacy of %4Alexadricaine Versus %2 Mepicaine-L for Infiltration Anesthesia in Extraction of Maxillary First Primary Molars in Children

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 5 Years – 7 Years
• Healthy volunteers: Accepted

Summary

The aim of the present study is to evaluate and compare the anesthetic efficacy of Alexadricaine versus Mepecaine-L infiltration anesthesia in children during extraction of badly decayed or unrestorable maxillary first primary molars.

Detailed description

To our knowledge, no clinical trials in literature have been done to compare anesthetic efficacy of 4% Articaine versus 2% Mepivacaine in pain management during extraction of badly decayed upper first primary molars. Thus, the purpose of the present study was to fill this knowledge gap. This trial will be held on a new brand of 4% articaine made in Egypt called Alexadricaine anesthetic solution where no clinical trials have been conducted on it yet in literature.

Conditions

• Local Anesthesia

Interventions

Type	Name	Description
DRUG	4% Articaine Hydrochloride with 1:100,000 Adrenaline	new Egyptian articane anesthetic solution.
DRUG	2% Mepivacaine Hydrochloride with 1:20,000 Levonordefrin	Mepecaine-L is the brand name of the Egyptian 2% Mepivacaine. It is the most commonly used anesthetic solution in Egypt due to its availability and its lower cost.

Timeline

• Start date: 2021-08-01
• Primary completion: 2021-09-30
• Completion: 2021-10-30
• First posted: 2020-07-20
• Last updated: 2023-03-14

Locations

1 site across 1 country: Egypt