Clinical Trials Directory

Trials / Recruiting

RecruitingNCT04475640

Cancer Genetic Testing in Ethnic Populations

GEMINI - Cancer Genetic Testing in Ethnic Populations

Status
Recruiting
Phase
N/A
Study type
Interventional
Enrollment
1,800 (estimated)
Sponsor
Mayo Clinic · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This clinical trial examines the integration of cancer genetic testing in various ethnic populations. Studying individuals and families at risk of cancer may help identify cancer genes and other persons at risk. The information from this study may provide an opportunity for cancer risk stratification and individualized screening in these ethnic populations.

Detailed description

PRIMARY OBJECTIVE: I. To determine the prevalence of genetic mutations in cancer patients from various ethnic populations seeking care at Mayo Clinic Arizona and Mayo Clinic Florida cancer clinics. SECONDARY OBJECTIVES: I. Perform a chart review to assess the impact of genetic testing as part of standard of oncology care: Ia. Determine prevalence of pathogenic germline mutation detected by multi-gene panel testing. Ib. Determine differences in germline mutation detection in these patients as compared to traditional guideline (National Comprehensive Cancer Network \[NCCN\]) based approach for genetic evaluation. OUTLINE: Patients undergo collection of blood or saliva sample for genetic testing.

Conditions

Interventions

TypeNameDescription
PROCEDUREBiospecimen CollectionUndergo collection of blood sample
OTHERGenetic TestingUndergo genetic testing

Timeline

Start date
2020-01-13
Primary completion
2028-10-15
Completion
2028-10-15
First posted
2020-07-17
Last updated
2026-04-02

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT04475640. Inclusion in this directory is not an endorsement.