Clinical Trials Directory

Trials / Unknown

UnknownNCT04475042

Stratified Treatment to Ameliorate Diastolic Left Ventricular Stiffness in Heart Failure With Preserved Ejection Fraction

Stratified Treatment to Ameliorate Diastolic Left Ventricular Stiffness in Heart Failure With Preserved Ejection Fraction. A 35-week, Single-center, Prospective, Double-blind, Controlled, Randomized, 2x2 Crossover, Interventional Phase II Study, Investigating the Effect of Treatment With Dapagliflozin 10mg od on Left Ventricular Distensibility in Patients With Early HFpEF.

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
26 (estimated)
Sponsor
Mariëlle Scheffer · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A 35-week, single-center, prospective, double-blind, controlled, randomized, 2x2 crossover, interventional Phase II study, investigating the effect of treatment with dapagliflozin 10mg od on Left Ventricular distensibility in patients with early HFpEF.

Conditions

Interventions

TypeNameDescription
DRUGDapagliflozin10mg od
DRUGPlaceboPlacebo

Timeline

Start date
2020-07-01
Primary completion
2021-11-01
Completion
2022-05-01
First posted
2020-07-17
Last updated
2020-09-22

Locations

1 site across 1 country: Netherlands

Source: ClinicalTrials.gov record NCT04475042. Inclusion in this directory is not an endorsement.