NCT04457063

Endothelial Cell Loss After Penetrating Keratoplasty

Endothelial Cell Loss Following Toric ICL Implantation for Correction of Myopia and Astigmatism After Penetrating Keratoplasty

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: Alexandria University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This work aimed at the assessment of corneal endothelial cell loss after toric ICL implantation for correction of myopia and astigmatism after penetrating keratoplasty.

Detailed description

Penetrating keratoplasty (PKP) is considered a safe and effective procedure.This work aimed at the assessment of corneal endothelial cell loss after toric ICL implantation for correction of myopia and astigmatism after penetrating keratoplasty.

Conditions

• Keratoconus

Interventions

Type	Name	Description
PROCEDURE	PKP	1. The horizontal axis was marked with a pointed marker at the slit lamp immediately before surgery. 2. TICL loading into the STAAR injector cartridge 3. Temporal clear corneal 3 mm incision \& 2-side ports then viscoelastic injection into the AC 4. Implantation of the TICL using the injector, then rotation according to the implantation diagram guided with Mendez protractor, and lastly placement of the haptics under the iris. 5. Pupil constriction with A.Ch. 6. Washing the viscoelastic \&Wound hydration. 7. Topical antibiotic steroids (Vigamox and Tobradex) 4 times /day for 3weeks

Timeline

• Start date: 2018-07-01
• Primary completion: 2020-06-01
• Completion: 2020-06-15
• First posted: 2020-07-07
• Last updated: 2020-07-07

Locations

1 site across 1 country: Egypt