Trials / Completed
CompletedNCT04450810
Role of NLRP3 in Periodontitis and Diabetes
Evaluation of Serum and Salivary NLRP3 in Periodontitis and Diabetes Patients
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 133 (actual)
- Sponsor
- University of Messina · Academic / Other
- Sex
- All
- Age
- 35 Years – 70 Years
- Healthy volunteers
- Accepted
Summary
NLRP3 plays a key role in endothelial function and may be a link for the known interaction of periodontitis and diabetes. The investigators compared the impact of gingival health, periodontitis (CP), diabetes or of both diseases (CP +diabetes) on saliva and serum NLRP3levels.
Detailed description
The aim of this study was to evaluate a possible association between NLRP3 and gingival health, periodontitis (CP), diabetes or of both diseases (CP +diabetes) on saliva and serum NLRP3 levels.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Observation of serum and salivary NLRP3 levels | Evaluation of serum and salivary NLRP3 levels |
Timeline
- Start date
- 2014-06-01
- Primary completion
- 2017-09-18
- Completion
- 2017-09-30
- First posted
- 2020-06-30
- Last updated
- 2021-01-26
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT04450810. Inclusion in this directory is not an endorsement.