NCT04430582

Cognition in Patients With Hypoglycemia, Without Diabetes

Pilot Study - Cognition in Patients With Hypoglycemia, Without Diabetes

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 22 (actual)
• Sponsor: Joslin Diabetes Center · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: —

Summary

The purpose of this study is to determine if there are differences in cognitive function (thinking) in individuals who have recurrent hypoglycemia (low blood sugars) following Roux-en-Y gastric bypass, compared with individuals who have also had a Roux-en-Y gastric bypass but do not have hypoglycemia.

Detailed description

This study will test the hypothesis that a history of recurrent hypoglycemia following gastric bypass is associated with differences in cognition (thinking), by analyzing results of cognitive testing in post-gastric bypass individuals with a history of hypoglycemia as compared to those without known hypoglycemia. This pilot study will identify cognitive domains of interest, as well as inform the development of a future battery of assessments, which could be replicated in a larger sample. Cognitive domains which will be assessed include: premorbid intelligence, memory, language, executive function, and psychomotor speed.

Conditions

• Hypoglycemia
• Cognition

Interventions

Type	Name	Description
OTHER	Cognitive Assessment (not diagnostic)	Cognitive testing will assess premorbid intelligence, working memory and attention, verbal memory and delayed memory, executive function, and psychomotor speed.
DIAGNOSTIC_TEST	ECG	ECG will take place during screening visit.

Timeline

• Start date: 2020-08-04
• Primary completion: 2021-08-04
• Completion: 2021-08-04
• First posted: 2020-06-12
• Last updated: 2024-11-04
• Results posted: 2024-11-04

Locations

1 site across 1 country: United States