NCT04430244

Deep Anterior Lamellar Keratoplasty Using Dehydrated Versus Standard Organ Culture Stored Donor Corneas

Deep Anterior Lamellar Keratoplasty Using Dehydrated Versus Standard Organ Culture Stored Donor Corneas: A Randomized Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Istituto Internazionale di Ricerca e Formazione in Oftalmologia · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The objective of this study is to assess the outcomes between deep anterior lamellar keratoplasty using dehydrated versus standard organ culture stored donor corneas.

Detailed description

Keratoconus is a common corneal disease characterized by progressive thinning and steepening resulting in significant visual impairment. With improved instrumentation and corneal imaging technology, deep anterior keratoplasty has been recognized as the preferred primary operative technique for cases of keratoconus requiring corneal transplantation. Since corneas preserved through organ culture remain viable only for up to 4 weeks, techniques that can extend storage of corneas have been explored. The objective of this study is to assess the outcomes between deep anterior lamellar keratoplasty using dehydrated versus standard organ culture stored donor corneas.

Conditions

• Keratoconus

Interventions

Type	Name	Description
PROCEDURE	Deep anterior lamellar keratoplasty	Deep anterior lamellar keratoplasty using dehydrated corneas
PROCEDURE	Deep anterior lamellar keratoplasty	Deep anterior lamellar keratoplasty using standard organ culture stored corneas

Timeline

• Start date: 2020-06-17
• Primary completion: 2023-05-01
• Completion: 2023-05-01
• First posted: 2020-06-12
• Last updated: 2020-07-07

Locations

1 site across 1 country: Italy