Trials / Terminated
TerminatedNCT04422743
Effect of Citicoline/Homotaurine on PERG in Primary Open Angle Glaucoma
Effect of the Fixed Combination Citicoline 500 mg Plus Homotaurine 50 mg on Pattern Electroretinogram in Well Controlled Primary Open Angle Glaucoma: A Multicenter, Prospective, Randomized, Single Blind, Cross-over Study
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 63 (actual)
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia · Academic / Other
- Sex
- All
- Age
- 40 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
the general purpose of the study is to evaluate the potential beneficial effects of supplementation of a fixed combination of Citicoline 500 mg plus Homotaurine 50 mg on retinal ganglion cells (RGCs) function in subjects with glaucoma by pattern electroretinogram.
Detailed description
Secondary objectives are to assess effects on visual acuity, visual field changes, Quality of Life perception (NEI VFQ25 questionnaire), and safety (Incidence of adverse events)
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Citicoline 500 mg plus Homotaurine 50 mg | Citicoline 500 mg plus Homotaurine 50 mg was added to topical therapy |
Timeline
- Start date
- 2018-01-25
- Primary completion
- 2020-09-11
- Completion
- 2020-09-11
- First posted
- 2020-06-09
- Last updated
- 2025-05-01
Locations
4 sites across 1 country: Italy
Source: ClinicalTrials.gov record NCT04422743. Inclusion in this directory is not an endorsement.