Clinical Trials Directory

Trials / Completed

CompletedNCT04404374

Treatment of Periodontal Intrabony Defects With A-PRF+ or EMD

Efficacy of a New-generation Platelet-rich Fibrin vs. Enamel Matrix Derivatives in the Treatment of Periodontal Intrabony Defects : a Randomized Clinical Trial

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
30 (actual)
Sponsor
Semmelweis University · Academic / Other
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

The aim of this randomized clinical trial was to clinically evaluate and compare the healing of intrabony defects after treatment with advanced platelet-rich fibrin (A-PRF+) to enamel matrix derivatives (EMD) in periodontitis patients.

Detailed description

Thirty (30) intrabony defects of 18 patients (9 males, 9 females) were randomly divided in two treatment groups: test (n = 15) and control (n = 15). The intrabony defects were filled with A-PRF+ (n=15) in the test group, respectively with EMD in the control group, and fixed with sutures to ensure wound closure and stability.

Conditions

Interventions

TypeNameDescription
PROCEDUREA-PRF/EMDComparing healing effect of an autologous and a xenogenic product

Timeline

Start date
2018-06-27
Primary completion
2020-06-30
Completion
2020-12-31
First posted
2020-05-27
Last updated
2021-03-05

Locations

1 site across 1 country: Hungary

Source: ClinicalTrials.gov record NCT04404374. Inclusion in this directory is not an endorsement.

Treatment of Periodontal Intrabony Defects With A-PRF+ or EMD (NCT04404374) · Clinical Trials Directory