Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT04388202

Leveraging EEG for Antidepressant Prediction With Sertraline and Escitalopram

Leveraging EEG for Antidepressant Prediction With Sertraline and Escitalopram (LEAP-SE): A Multicenter, Randomized, Blinded Outcome Study of EEG-guided Treatment With Sertraline Versus Escitalopram in Adults With Major Depressive Disorder

Status
Withdrawn
Phase
Phase 4
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Alto Neuroscience · Industry
Sex
All
Age
22 Years – 85 Years
Healthy volunteers
Not accepted

Summary

The LEAP-SE study will be conducted to validate the utility of EEG biomarkers as an aid to antidepressant treatment selection in adults with MDD.

Detailed description

The LEAP-SE study is an 8-week, multicenter, randomized, blinded study to evaluate the performance of EEG-based biomarkers in predicting treatment outcome. Study participants will be randomized in a 1:1 ratio to receive either sertraline or escitalopram and followed for 8 weeks.

Conditions

Interventions

TypeNameDescription
DRUGSertralineFDA approved antidepressant
DRUGEscitalopramFDA approved antidepressant

Timeline

Start date
2020-10-15
Primary completion
2023-05-30
Completion
2023-05-30
First posted
2020-05-14
Last updated
2020-10-19

Source: ClinicalTrials.gov record NCT04388202. Inclusion in this directory is not an endorsement.