Trials / Unknown
UnknownNCT04387357
Multimodal Imaging in the Study of Disorientation in the Hospital
Multimodal Imaging in Alzheimer's Disease and Other Neurodegenerative Diseases
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (estimated)
- Sponsor
- University Medical Center Rostock · Academic / Other
- Sex
- All
- Age
- 50 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to investigate whether markers of brain structure and function from MRI are associated with different levels of spatial orientation and gait parameters in people with mild cognitive impairment or dementia due to Alzheimer's disease when walking through a real world environment.
Detailed description
This is an experimental cross-sectional study which primarily aims at identifying characteristic features of spatial disorientation among people with mild cognitive impairment and dementia. The features of interest are motion and physiological related changes that occur during instances of spatial disorientation, which will be derived from wearable sensors. Additionally, brain structure and functional connectivity changes associated with different levels of spatial orientation and gait parameters will also be investigated through resting-state functional imaging.
Conditions
Timeline
- Start date
- 2019-10-01
- Primary completion
- 2021-06-01
- Completion
- 2021-06-30
- First posted
- 2020-05-13
- Last updated
- 2020-05-13
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT04387357. Inclusion in this directory is not an endorsement.