NCT04382105

Evaluation of Saliva IL-6 Levels and Periodontitis

Association Between Salivary IL-6 and Extent of Periodontitis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 287 (actual)
• Sponsor: University of Messina · Academic / Other
• Sex: All
• Age: 35 Years – 65 Years
• Healthy volunteers: —

Summary

The aim of this study was to analyze the association between salivary IL-6 levels in patients with periodontitis. Furthermore, the objective was to determine if the periodontitis influenced salivary IL-6 levels

Detailed description

Forty-nine patients with periodontitis and 47 healthy subjects (HS) were enrolled in the present study. Enrolled patients were examined and characterized for clinical and blood samples analysis, and salivary IL-6 levels. The Spearman Correlation Test and Jonckheere-Terpstra Test were applied in order to assess the interdependence between salivary IL-6 levels and clinical periodontal parameters.

Conditions

• Periodontal Diseases

Interventions

Type	Name	Description
OTHER	Observation of salivary IL-6 levels	Observation of salivary IL-6 levels and correlation of salivary IL-6 levels with periodontal disease

Timeline

• Start date: 2015-11-08
• Primary completion: 2019-09-15
• Completion: 2019-09-25
• First posted: 2020-05-11
• Last updated: 2020-11-24

Locations

1 site across 1 country: Italy