NCT04378907

Assessing Electronic Cigarette Nicotine Flux

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 33 (actual)
• Sponsor: Virginia Commonwealth University · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine differences in nicotine delivery, use behavior, carbon monoxide delivery, subjective effects, and physiological effects, when cigarette smokers use an electronic cigarette with constant device settings and different e-liquid concentrations.

Detailed description

Only one arm enrolled.

Conditions

• Electronic Cigarette Use

Interventions

Type	Name	Description
OTHER	Cigarette Smoker/ECIG users: 0 mg/ml nicotine concentration	ECIG LAB SESSION: 30 watts, 0 mg/ml nicotine concentration. During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
OTHER	Cigarette Smokers/ECIG users: 6 mg/ml nicotine concentration	ECIG Lab Session, 30 watts, 6 mg/ml nicotine concentration. During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
OTHER	Cigarette Smokers/ECIG users: 15 mg/ml nicotine concentration	ECIG Lab Session, 30 watts, 15 mg/ml nicotine concentration. During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
OTHER	Cigarette Smokers/ECIG users: 30 mg/ml nicotine concentration	ECIG Lab Session, 30 watts, 30 mg/ml nicotine concentration During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.

Timeline

• Start date: 2021-01-05
• Primary completion: 2023-02-01
• Completion: 2023-02-01
• First posted: 2020-05-07
• Last updated: 2026-02-04
• Results posted: 2026-02-04

Locations

1 site across 1 country: United States