NCT04374617

Risk of Venous Thromboembolism in Critically Ill Patients With Severe COVID-19

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 230 (actual)
• Sponsor: Hospital Universitari Vall d'Hebron Research Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Severe COVID-19 patients at a high risk of venous thromboembolism. We studied patients in 2 intensive care units of university hospitals in Barcelona and Badalona, Spain. We performed a cut-off screening of deep venous thrombosis (DVT) with bilateral duplex ultrasound to 230 patients.

Detailed description

SARS-CoV-2 infection has been associated with coagulation disorders and increased risk of venous thromboembolism (VTE). The aim of the study is to determine the cumulative incidence of VTE in critically ill patients with COVID-19 and its impact on prognosis. Methods Cohort study of critically ill patients due to COVID-19. A bilateral venous compression (CUS) ultrasound screening of the lower extremities was performed during a cut-off period in 2 intensive care units of university hospitals in Spain. Asymptomatic and symptomatic VTE were registered: pulmonary embolism (PE) (diagnosed by CT-angiography) and deep venous thrombosis (DVT). The characteristics of the patients, results of their blood tests and their evolution after 7 days of follow-up were recorded.

Conditions

• COVID-19
• Critical Illness
• Venous Thromboembolism
• Venous Thromboses
• Venous Thromboses, Deep
• Venous Thrombosis Pulmonary
• Pulmonary Embolism
• Pulmonary Embolism and Thrombosis
• Sars-CoV2
• SARS-CoV Infection

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Duplex ultrasound and Computed Tomography Angiography	All venous thromboembolisms suspected will diagnosed with ultrasound and CT-angiography

Timeline

• Start date: 2020-04-01
• Primary completion: 2020-04-25
• Completion: 2020-05-01
• First posted: 2020-05-05
• Last updated: 2020-05-06

Locations

3 sites across 1 country: Spain