NCT04370353

Impact of Cocoa Flavanols on Pulmonary Oxygen Uptake Kinetics and Exercise Tolerance in Sedentary Middle-aged Adults

Investigating the Impact of Cocoa Flavanol Supplementation on Pulmonary Oxygen Uptake Kinetics and Exercise Tolerance in Sedentary Middle-aged Adults

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: Liverpool John Moores University · Academic / Other
• Sex: All
• Age: 35 Years – 55 Years
• Healthy volunteers: Accepted

Summary

In recent years, there has been significant interest in dietary flavonoids (biologically active plant-derived compounds) as potential therapeutics. This is due to the capacity of flavonoids to enhance processes related to energy metabolism and cardiovascular health. We are interested in implementing a short-term supplementation regime (daily cocoa-flavanoid ingestion), in order to explore the possible beneficial effects of flavonoid-based interventions on responses to exercise. Hence, the objective of our study is to examine the impact of short term cocoa-flavanoid supplementation on processes related to energy use (oxygen utilisation). Our aim is to develop a novel intervention which improves cardiovascular health and enhances exercise tolerance.

Conditions

• Aging
• Sedentary Behavior

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Cocoa flavanols	Flavonoid-rich cocoa powder, containing 100mg total flavanols per 316mg.
DIETARY_SUPPLEMENT	Placebo supplement	Microcrystalline filler, containing 0mg total flavanols.

Timeline

• Start date: 2018-04-01
• Primary completion: 2019-06-07
• Completion: 2019-06-07
• First posted: 2020-04-30
• Last updated: 2020-04-30

Locations

1 site across 1 country: United Kingdom