Clinical Trials Directory

Trials / Completed

CompletedNCT04365764

Effect of Treatments in Patients Hospitalized for Severe COVID-19 Pneumonia: a Multicenter Cohort Study

Status
Completed
Phase
Study type
Observational
Enrollment
400 (actual)
Sponsor
Groupe Hospitalier Pitie-Salpetriere · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

Several treatments have been used in during the Covid-19 pandemic of 2020. Using patients' registries from several hospitals in Paris, the investigators retrospectively analyzed associations between specific treatments, including but not limited to vaccines targeted against SARS-CoV-2, hydroxychloroquine, azithromycin, remdesivir, baricitinib, tocilizumab, sarilumab, lopinavir/ritonavir and oseltamivir; and clinical outcomes including, death and mechanical ventilation.

Detailed description

Several treatments have been used in during the Covid-19 pandemic of 2020. Using patients' registries from several hospitals in Paris, the investigators retrospectively analyzed associations between specific treatments, including but not limited to vaccines targeted against SARS-CoV-2, hydroxychloroquine, azithromycin, remdesivir, baricitinib, tocilizumab, sarilumab, lopinavir/ritonavir and oseltamivir; and clinical outcomes including, death and mechanical ventilation. Other outcomes of interest include: acute kidney injury, encephalopathy, need for intensive care unit transfers.

Conditions

Timeline

Start date
2020-03-14
Primary completion
2022-12-31
Completion
2022-12-31
First posted
2020-04-28
Last updated
2023-04-21

Locations

2 sites across 1 country: France

Source: ClinicalTrials.gov record NCT04365764. Inclusion in this directory is not an endorsement.