NCT04360070

The Application of Ketamine for Sedation in Patients With Cardiac Arrest - - KetCat (KETamine in Cardiac ArresT) Study

The Application of Ketamine for Sedation in Patients With Cardiac Arrest: Feasibility, Safety, and Potential Impact on Neurological Outcomes

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Fraser Health · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

Recent evidence suggests ketamine may attenuate harmful cellular cascades taking place after brain injury that result in permanent damage. The investigators are interested in researching the application of this in the setting of cardiac arrest. Following cardiac arrest, the brain is deprived oxygen for a period of time, leading to the imitation of these harmful cellular processes. The investigators hypothesize that patients who receive ketamine as part of their standard sedation procedures during cardiac arrest treatment have better neurological functioning compared to those who do not.

Conditions

• Cardiac Arrest, Out-Of-Hospital
• Ketamine
• Neurologic Manifestations

Interventions

Type	Name	Description
DRUG	Ketamine Hydrochloride	Parenteral General Anesthetic

Timeline

• Start date: 2022-02-28
• Primary completion: 2023-12-09
• Completion: 2023-12-12
• First posted: 2020-04-24
• Last updated: 2023-01-10

Locations

1 site across 1 country: Canada