Clinical Trials Directory

Trials / Completed

CompletedNCT04350606

A Study to Assess Efficacy and Safety of PF-06462700 in Japanese Participants With Aplastic Anemia

A MULTICENTER, OPEN-LABEL, SINGLE-ARM STUDY TO ASSESS THE EFFICACY AND SAFETY OF PF-06462700 ADMINISTERED INTRAVENOUSLY AT 40 MG/KG/DAY FOR 4 DAYS IN JAPANESE PARTICIPANTS WITH MODERATE AND ABOVE APLASTIC ANEMIA

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
3 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
2 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to assess the efficacy and safety of PF-06462700 administered intravenously at 40 mg/kg/day for 4 days in Japanese participants with moderate and above aplastic anemia for making an approval application in Japan.

Conditions

Interventions

TypeNameDescription
BIOLOGICALPF-06462700PF-06462700 is classified as an immunosuppressant/ immunosuppressive agent. It is the purified, concentrated, and sterile gamma globulin, primarily monomeric immunoglobulin G (IgG), from hyperimmune serum of horses that are immunized with human thymus lymphocytes.

Timeline

Start date
2020-07-25
Primary completion
2021-01-22
Completion
2021-04-19
First posted
2020-04-17
Last updated
2022-04-27
Results posted
2022-04-27

Locations

3 sites across 1 country: Japan

Regulatory

Source: ClinicalTrials.gov record NCT04350606. Inclusion in this directory is not an endorsement.

A Study to Assess Efficacy and Safety of PF-06462700 in Japanese Participants With Aplastic Anemia (NCT04350606) · Clinical Trials Directory