NCT04347902

Lipid Emulsions and Liver Function - Results After 5 Years.

Intravenous Lipid Emulsions and Liver Function in Adult Chronic Intestinal Failure Patients: New Results After 5 Years.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 65 (actual)
• Sponsor: Stanley Dudrick's Memorial Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Intravenous lipid emulsion (ILE) is an essential component of parenteral nutrition (PN), but also one of the key risk factors for development of intestinal failure associated liver disease (IFALD). The aim of the study was to analyse the influence of ILEs on liver function during long term PN.

Detailed description

Intravenous lipid emulsion (ILE) is an essential component of parenteral nutrition (PN), but also one of the key risk factors for development of intestinal failure associated liver disease (IFALD). Despite of many commercially available ILEs with hypothetically different impact on liver, a direct comparison of them has never been performed. Therefore the aim of the study was to analyse the influence of ILEs on liver function during long term PN. Ths study is a continuation of the previous trial, NCT03044639.

Conditions

• Liver Failure
• Parenteral Nutrition-Related Hepatitis

Interventions

Type	Name	Description
DRUG	Intravenous Lipid Emulsion	Various types of intravenous lipids

Timeline

• Start date: 2016-01-01
• Primary completion: 2020-03-01
• Completion: 2020-04-01
• First posted: 2020-04-15
• Last updated: 2020-04-17

Locations

1 site across 1 country: Poland