NCT04346784

The Effect of Emotional Working Memory Training on Preventing Depression Occurrence

A Randomized, Double-blind, Placebo-Controlled Evaluation of the Efficacy of Emotional Working Memory Training in the Prevention Treatment of Depressive Symptoms

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 110 (actual)
• Sponsor: Hunan Normal University · Academic / Other
• Sex: All
• Age: 16 Years – 21 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to test whether emotional working memory training and attention bias modification training are an effective neurobehavioral therapy to prevent the occurrence of depression .That is whether emotional working memory training and attention bias modification training are superior to placebo in preventing the occurrence of depression over 1 year after training.

Detailed description

Attentional bias has been theorized to play a critical role in the onset and maintenance of depression. Attentional bias modification training (ABMT), an experimental paradigm that uses training to induce adaptive attentional bias, was developed to test the causal model and this has therapeutic implications in depression.To test the effect of ABMT on treatment of depressive symptoms, a randomized, double-blind, placebo and blank controlled trial is conducted in college students who are experiencing mild-to-severe symptoms of depression.

Conditions

• Depressive Symptoms

Interventions

Type	Name	Description
BEHAVIORAL	maintaining positive working memory training	Participants complete 10 sessions of maintaining positive working memory training during a two-week period. Each session consists of 15 blocks.
BEHAVIORAL	repressing negative working memory training	Participants complete 10 sessions of repressing negative working memory training during a two-week period. Each session consists of 15 blocks.
BEHAVIORAL	Positive ABMT	Participants complete 8 sessions of attention bias modification training (ABMT) during a two-week period. Each session consists of 218 trials, and the time to complete a training session is 12 minutes.
BEHAVIORAL	Positive placebo ABMT	Participants complete 8 sessions of attention bias modification training (ABMT) during a two-week period. Each session consists of 218 trials, and the time to complete a training session is 12 minutes

Timeline

• Start date: 2019-12-18
• Primary completion: 2021-01-10
• Completion: 2021-01-10
• First posted: 2020-04-15
• Last updated: 2020-04-15

Locations

1 site across 1 country: China