NCT04345159

Association Between Long-term Hydroxychloroquine Treatment and Outcome of a History of Symptoms Suggestive of COVID-19 Infection During the Epidemic Period in France in Patients With Autoimmune Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 572 (actual)
• Sponsor: Fondation Ophtalmologique Adolphe de Rothschild · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This epidemiological, transversal, cohort study aims to determine the potential influence of an active long-term hydroxychloroquine intake over the prevalence of a history of symptoms evocative of a COVID-19 infection in patients with a history of systemic lupus erythematosus, rheumatoid arthritis, Sjogren's syndrome or psoriatic arthritis, during the epidemic period in France. The information is gathered using a standardized questionnaire, by phone call.

Conditions

• SARS-CoV-2
• Systemic Lupus Erythematosus
• Rheumatoid Arthritis
• Sjogren's Syndrome
• Psoriatic Arthritis

Interventions

Type	Name	Description
OTHER	Questionnaire by phone call	2 questionnaires : at inclusion and 4 months later. The exposure to hydroxychloroquine and the history of autoimmune disease is determined during the phone call along with other exposure factors. The symptoms presented by the patient are classified in "Suggestive of a COVID-19 infection" or "Not suggestive of COVID-19 infection" by a team of internists and infectious diseases specialists, by studying the questionnaires after the completion in a blind-manner regarding the hydroxychloroquine intake.

Timeline

• Start date: 2020-04-17
• Primary completion: 2020-11-30
• Completion: 2020-11-30
• First posted: 2020-04-14
• Last updated: 2021-01-07

Locations

1 site across 1 country: France