NCT04342585

Comparison Between Vaginal Pessary and Progestogen in Twin Pregnancy With Short Cervical Length

Randomised Controlled Trial Comparing Vaginal Pessary and Progestogen as an Intervention in Twin Pregnancy With Short Cervical Length to Prevent Spontaneous Preterm Birth

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 142 (actual)
• Sponsor: National University of Malaysia · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

A randomized clinical trial comparing vaginal progestogen and vaginal pessary as an intervention for twin pregnancies with short cervical length.

Detailed description

This is a randomized controlled trial to compare women with twin pregnancies and diagnosed with asymptomatic short cervical length. Two types of interventions will be compared i.e vaginal progestogen and vaginal pessary.

Conditions

• Preterm Birth

Interventions

Type	Name	Description
DRUG	Micronised vaginal progesterone	A diary will be given to participants to ensure compliance.
DEVICE	Vaginal pessary	The internal diameter size will be decided based on the clinical assessment of the cervix.

Timeline

• Start date: 2019-10-01
• Primary completion: 2022-09-30
• Completion: 2022-09-30
• First posted: 2020-04-13
• Last updated: 2024-01-23

Locations

1 site across 1 country: Malaysia