Trials / Completed
CompletedNCT04335162
Cardiovascular Complications and COVID-19 (CovCardioVasc-Study)
Cardiovascular Complications in Patients With COVID-19
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 198 (actual)
- Sponsor
- Centre Hospitalier Universitaire de Nice · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- —
Summary
Patients with COVID-19 in the Intensive Care Unit (ICU) or hospitalized with severe form have a poor prognosis (almost 30% rate of death). They present often a high cardiovascular risk profile (almost 30% of hypertension and 19% of diabetes). Troponin has been described to be elevated in a high proportion of patients (one fifth of all patients and 50% of non-survivors) suggesting the possibility of cardiomyopathies. High levels of DDimers (81% of non survivors) and fibrin degradation products are also associated with increased risk of mortality suggesting also the possibility of venous thromboembolism. Therefore, screening for cardiomyopathies and venous thromboembolism could represent an important challenge for patients with COVID-19 management.
Conditions
- COVID
- Acute Coronary Syndrome
- Myocardial Infarction
- Myocarditis
- Venous Thromboembolism
- Deep Vein Thrombosis
- Pulmonary Embolism
Timeline
- Start date
- 2020-02-28
- Primary completion
- 2021-08-31
- Completion
- 2021-08-31
- First posted
- 2020-04-06
- Last updated
- 2025-04-03
Locations
8 sites across 1 country: France
Source: ClinicalTrials.gov record NCT04335162. Inclusion in this directory is not an endorsement.