Trials / Withdrawn
WithdrawnNCT04321603
Altering Mechanisms of Frailty in Persons Living With HIV Aged 50 to 65
- Status
- Withdrawn
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 0 (actual)
- Sponsor
- University of Maryland, Baltimore · Academic / Other
- Sex
- All
- Age
- 50 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
People living with HIV are living longer as their disease is controlled with antiretroviral medications. Yet they are experiencing frailty more often and more than ten years earlier than those without HIV. In elderly persons without HIV, frailty is associated with decreased muscle strength and chronic inflammation. Less is known about what is driving early frailty in HIV or effective prevention measures for aging adults with HIV. It may be that having HIV infection impairs energy production by mitochondria within the cells and contributes to the muscle weakness and inflammation accompanying frailty in people living with HIV . This study will examine the impact of six weeks of moderately paced walking on energy production in the cells, inflammation markers and frailty scores in people living with well-controlled HIV who are aged 50 to 65.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Walking | Moderately paced walking of approximately 100 steps/minute for 30 minutes three times weekly for six weeks. |
Timeline
- Start date
- 2020-05-30
- Primary completion
- 2020-05-30
- Completion
- 2020-05-30
- First posted
- 2020-03-25
- Last updated
- 2021-08-11
Source: ClinicalTrials.gov record NCT04321603. Inclusion in this directory is not an endorsement.