NCT04303767

The Effect of Casein Phosphopeptide Amorphous Calcium Phosphate on Affected Dentine

The Reparative Effect of Casein Phosphopeptide Amorphous Calcium Phosphate Varnish on Caries Affected Dentine in Primary Teeth (Randomized Controlled Clinical Trial)

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 132 (estimated)
• Sponsor: Hams Hamed Abdelrahman · Academic / Other
• Sex: All
• Age: 6 Years – 11 Years
• Healthy volunteers: Accepted

Summary

Teeth selected for intervention with Atraumatic Restorative Treatment will receive Glass Ionomer restorations (control) or MI varnish (test) before receiving the Glass Ionomer restoration

Detailed description

Patients selected to participate in the study will be randomly assigned into 2 groups. Group 1 (test): who will receive casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP) + ART in the teeth selected, excavating only the caries infected dentine and preserving the caries affected dentine. Group 2 (control): Who will receive ART only in the teeth selected, excavating only the caries infected dentine and preserving the caries affected dentine.

Conditions

• Caries,Dental

Interventions

Type	Name	Description
DRUG	Casein phosphopeptide amorphous calcium phosphate	varnish containing calcium and phospate ions which act as a source for tooth remineralization
PROCEDURE	Atraumatic restorative treatment	excavation of dental caries and restoring with light cured Glass Ionomer Restoration

Timeline

• Start date: 2020-03-01
• Primary completion: 2020-08-01
• Completion: 2021-02-01
• First posted: 2020-03-11
• Last updated: 2020-03-11

Locations

1 site across 1 country: Egypt