NCT04298996

Effect of Passive Smoking on Oxidative Stress and Dental Caries in Children

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 180 (actual)
• Sponsor: Merve Erkmen Almaz · Academic / Other
• Sex: All
• Age: 6 Years – 12 Years
• Healthy volunteers: Accepted

Summary

The purpose of the present study was to determine the effect of passive smoking on oxidative stress and dental caries in children.A total of 180 children were included to the study as follows; 90 children exposed to passive smoking, and 90 children in the control group (unexposed controls). Also demographic data were recorded (age, gender, parental education levels, child's tooth-brushing habit and child's daily dietary sugar exposure, family income). Dental examination of children were performed and caries prevalence of the patients were recorded. Unstimulated saliva samples were collected from children. Saliva 'cotinine levels' and oxidative stress markers 'total antioxidant status' (TAS), and' total oxidant status' (TOS) were evaluated by using Enzyme-linked immunosorbent assay (ELISA). The obtained data parameters of the two groups were evaluated and comparison was performed.

Conditions

• Oxidative Stress
• Dental Caries
• Passive Smoking

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	taking saliva samples to determine oxidative stress markers TAS and TOS

Timeline

• Start date: 2016-11-16
• Primary completion: 2018-04-15
• Completion: 2018-08-15
• First posted: 2020-03-06
• Last updated: 2020-03-09