Trials / Completed
CompletedNCT04296006
Neurobehavioral Mechanisms of Cocaine Choice
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 15 (actual)
- Sponsor
- Joshua A. Lile, Ph.D. · Academic / Other
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Not accepted
Summary
The objective of this protocol is to use a drug-vs-money choice task, reinforcement learning modeling and fMRI to determine the neurobehavioral and neurobiological decision-making "profile" associated with the decision to take cocaine and the reduced cocaine choice that occurs during a behavioral intervention (alternative money reinforcer) that models contingency management.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Money | Three money values offered as alternatives to cocaine. |
| DRUG | Cocaine HCl | 3 mg/70 kg is available as an alternative to money. |
Timeline
- Start date
- 2021-01-15
- Primary completion
- 2025-02-01
- Completion
- 2025-02-01
- First posted
- 2020-03-05
- Last updated
- 2025-04-03
- Results posted
- 2025-04-03
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT04296006. Inclusion in this directory is not an endorsement.