NCT04239274

Spectral Correlates of Impulsivity in Patients With Traumatic Brain Injury

Spectral Correlates of Impulsivity in Patients With Traumatic Brain Injury: A Study of the Effect of Transcranial Electrical Stimulation of the Ventrolateral Prefrontal Cortex on Response Inhibition

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Medical University of South Carolina · Academic / Other
• Sex: All
• Age: 25 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Transcranial electrical stimulation (tES) is a non-invasive form of brain stimulation that has previously been to shown to have therapeutic potential in traumatic brain injury (TBI) patients. In this study, the study team will use a brain activity monitor (electroencephalogram, EEG) and a computer-based task to observe the effects of different forms of tES, like transcranial direct current stimulation (tDCS) and transcranial pulsed current stimulation (tPCS), on impulse control and sustained attention in people with TBI. Additionally, the study team will measure how much tDCS and tPCS affect the brain activity of a specific area of the brain associated with impulse control and attention. Problems with response inhibition have been shown to make rehabilitation more difficult for people with TBI. It also reduces social functioning and can also negatively affect job performance, which ultimately lead to a decreased quality of life. A better understanding of the effects of tES in TBI patients could be informative in finding out what its therapeutic potential is for this population.

Conditions

• Traumatic Brain Injury

Interventions

Type	Name	Description
DEVICE	transcranial direct current stimulation	Subjects in this arm will receive one session of tDCS for 20 minutes at 2.0 milliamps.
DEVICE	transcranial pulsed current stimulation	Subjects in this arm will receive one session of tPCS for 20 minutes at 2.0 milliamps.
DEVICE	Sham-no stimulation	Subjects in this arm will receive one session of sham for 20 minutes.

Timeline

• Start date: 2020-01-01
• Primary completion: 2021-01-01
• Completion: 2021-01-01
• First posted: 2020-01-27
• Last updated: 2022-01-04