NCT04237662

Enamel Matrix Derivatives & Periodontal Therapy in Diabetic Patients

The Impact of Enamel Matrix Derivatives on Periodontal Healing in Diabetic Patients After Non-Surgical Periodontal Therapy

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 38 (estimated)
• Sponsor: University of Pisa · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare periodontal treatment with or without the adjunct of an enamel matrix derivative in terms of periodontal healing in diabetic patients.

Detailed description

Patients with periodontitis will be randomly allocated to two groups. In both groups, periodontal root instrumentation will be performed. In the test group, an additional flapless application of enamel matrix derivatives will be granted for sites with pockets deeper than 5 mm. Metabolic glucose control as measured through blood testing and local parameters of periodontal health will be measured at baseline and three months after treatment completion.

Conditions

• Periodontal Diseases

Interventions

Type	Name	Description
PROCEDURE	Root Instrumentation	Instrumentation of the root surface in order to achieve debridement
DEVICE	Enamel Matrix Derivative application	Enamel Matrix Derivative will be applied in the sites with at least 6 mm of pocket depths

Timeline

• Start date: 2021-01-01
• Primary completion: 2023-01-01
• Completion: 2023-12-31
• First posted: 2020-01-23
• Last updated: 2020-11-04

Locations

1 site across 1 country: Italy