Clinical Trials Directory

Trials / Completed

CompletedNCT04235309

Physical Resilience: Indicators and Mechanisms in the Elderly (PRIME) Collaborative Phase 2

Status
Completed
Phase
Study type
Observational
Enrollment
297 (actual)
Sponsor
Duke University · Academic / Other
Sex
All
Age
60 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to examine underlying physical resilience (the ability to bounce back) in response to a specific stressor (total knee replacement).

Detailed description

In general, a person's specific resilience (ability to bounce back from a stressor) is thought to be dependent upon that person's specific biological and genetic makeup. However, these specific elements remain poorly understood. The purpose of this study is to identify important predictors and characteristics of resilience in response to a total knee replacement by examining baseline resilience (prior to surgery) and post-surgical resilience at multiple time points, allowing us to track resilience outcomes over time.

Conditions

Timeline

Start date
2020-02-27
Primary completion
2023-10-30
Completion
2023-10-30
First posted
2020-01-21
Last updated
2025-12-08

Locations

3 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT04235309. Inclusion in this directory is not an endorsement.