Trials / Enrolling By Invitation
Enrolling By InvitationNCT04234139
Cohort/Ethics Study of Patients With Severe Alcoholic Hepatitis Undergoing Early Liver Transplantation
- Status
- Enrolling By Invitation
- Phase
- —
- Study type
- Observational
- Enrollment
- 300 (estimated)
- Sponsor
- Johns Hopkins University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to develop a clinical understanding of early liver transplantation (ELT) for patients with severe alcoholic hepatitis (SAH) and identify the public's opinion regarding this practice.
Detailed description
The research study is designed to improve the investigators' understanding of early liver transplantation for patients with severe alcoholic hepatitis. The goal of this research is twofold: 1. Establish a knowledge base necessary for appropriate liver transplant candidate selection by quantifying post-ELT mortality for SAH and compare to outcomes to liver transplantation for other indications 2. Develop an ethical framework for implementation of these transplants for SAH based on the opinions of healthcare providers and the general public.
Conditions
- Liver Diseases, Alcoholic
- Alcohol-Related Disorders
- Transplant; Failure, Liver
- Transplant; Complication, Rejection
- Liver Diseases
- Hepatitis, Alcoholic
- Alcohol-Induced Disorders
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | liver transplant | solid organ transplant |
Timeline
- Start date
- 2020-04-01
- Primary completion
- 2028-12-31
- Completion
- 2029-12-31
- First posted
- 2020-01-21
- Last updated
- 2025-12-16
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT04234139. Inclusion in this directory is not an endorsement.