NCT04232956

Invasive Pulmonary Aspergillosis and Severe Influenza

Is Invasive Pulmonary Aspergillosis a Common Complication of Severe Influenza ?

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 478 (actual)
• Sponsor: University Hospital, Brest · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Invasive pulmonary aspergillosis (IPA) has been reported in critically ill patients with influenza infection with a highly variable incidence between 1 to 21%. Studies investigating IPA in critically ill patients with influenza infection suffer limitations in their methods. It remains unknown whether patients with influenza are more at risk of IPA than other patients hospitalized in intensive care unit and whether patients with influenza who develop IPA have specific risk factors for this infection. Our study aims to determine the incidence of IPA in a large multicenter cohort and to identify risk factors for IPA in these patients.

Conditions

• Aspergillosis
• Influenza
• Critical Illness

Timeline

• Start date: 2018-07-27
• Primary completion: 2018-11-05
• Completion: 2018-11-05
• First posted: 2020-01-18
• Last updated: 2020-01-18

Locations

4 sites across 1 country: France