Clinical Trials Directory

Trials / Completed

CompletedNCT04221802

Patient-reported Outcomes in Real-world Use of Benralizumab in Patients With Severe Eosinophilic Asthma in Belgium

A Multicentre Single Arm Observational Prospective Study to Assess Demographic Characteristics Burden of Disease PRO's in Uncontrolled, Severe Eosinophilic Asthma Patients Aged 18y or Older and Qualifying for Treatment With Benralizumab in BE

Status
Completed
Phase
Study type
Observational
Enrollment
76 (actual)
Sponsor
AstraZeneca · Industry
Sex
All
Age
18 Years – 99 Years
Healthy volunteers
Not accepted

Summary

This study aims to assess health and quality of life outcomes in patients treated with benralizumab, within a Belgian Real-World setting. To prove the clinical value of benralizumab in a Real-World setting, the study will document the effect of benralizumab within a time frame of 112 weeks after initiation of treatment.

Detailed description

The aim and objective of this single arm, prospective observational study is to provide supporting RWE on the symptom relief of asthma patients qualified for benralizumab therapy in Belgium. The PRO measures consist of the Asthma Control Questionnaire (ACQ 6) as well as Patient Global Impression of Change and Severity (PGI-C and PGI-S), healthcare resource utilization (HCRU) and treatment satisfaction (TSQM-9). In addition change in daily OCS use and rate of exacerbations after initiation of benralizumab in real-world setting will be assessed

Conditions

Timeline

Start date
2019-12-23
Primary completion
2024-05-13
Completion
2024-05-13
First posted
2020-01-09
Last updated
2025-05-06

Locations

10 sites across 1 country: Belgium

Source: ClinicalTrials.gov record NCT04221802. Inclusion in this directory is not an endorsement.

Patient-reported Outcomes in Real-world Use of Benralizumab in Patients With Severe Eosinophilic Asthma in Belgium (NCT04221802) · Clinical Trials Directory