NCT04219592

IgG-4 Levels in Systemic Sclerosis

Comparing IgG-4 Levels in Systemic Sclerosis Patients vs. Healthy Controls

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 154 (actual)
• Sponsor: Meir Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Accepted

Summary

This is an observational - non interventional study. The investigators will compare IgG4 levels of 80 healthy donors (from Israel blood bank - MDA) and 80 Systemic Sclerosis patients from Meir Medical Center.

Detailed description

IgG4 levels will be obtained from medical records of 80 SSc patients between the years 2000-2019. These will be compared to IgG4 levels from sera of 80 healthy donors (from Israel blood-bank - MDA). Correlations between IgG4 levels and the following will be made: age, sex, disease type (limited or diffused SSc), disease duration, medications.

Conditions

• Systemic Sclerosis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	IgG4 measurement (non-interventional, just obtaining data from medical records)	IgG4 measurement in mg/dL

Timeline

• Start date: 2019-05-30
• Primary completion: 2024-09-30
• Completion: 2024-10-30
• First posted: 2020-01-07
• Last updated: 2025-05-16

Locations

1 site across 1 country: Israel