NCT04217239

A Comparison Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy

A Comparison of Short-term and Long- Term Outcomes Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 272 (actual)
• Sponsor: The Second Hospital of Shandong University · Academic / Other
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Surgery is still the main treatment for esophageal cancer, however, the complication and mortality rate of open esophagectomy is high. As a result, the thoracoscopic- laparoscopic minimally invasive esophagectomy (MIE) was developed. The MIE mainly comprised two surgical approaches: MIE McKeown approach (cervical anastomosis) and MIE Ivor-Lewis approach (intrathoracicanastomosis). The MIE with intrathoracic anastomosis (Ivor-Lewis) is increasingly used for the treatment of mid and lower esophageal cancers. Our study is trying to compare the safety, feasibility, and short-term and long- term outcomes between MIE Ivor-Lewis approach and MIE McKeown approach for the treatment of lower thoracic esophageal cancer and esophageal- gastric junction.

Conditions

• Esophageal Cancer

Interventions

Type	Name	Description
PROCEDURE	MIE Ivor- Lewis	minimally invasive esophagectomy (MIE) with intrathoracic anastomosis
PROCEDURE	MIE McKeown	minimally invasive esophagectomy (MIE) with cervical anastomosis

Timeline

• Start date: 2020-01-01
• Primary completion: 2024-06-30
• Completion: 2024-06-30
• First posted: 2020-01-03
• Last updated: 2026-02-05

Locations

1 site across 1 country: China