NCT04212559

Hemodynamic Effects of Negative Pressure Ventilation in Chronic Obstructive Pulmonary Disease

Hemodynamic Effects of Negative Pressure Ventilation in Chronic Obstructive Pulmonary Disease Assessed Using Non-Invasive Electrical Cardiometry

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 30 (actual)
• Sponsor: Fu Jen Catholic University · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

Negative pressure ventilation (NPV) is a non-invasive ventilation mode which provide better lung expansion. The major complication of NPV is decrease blood pressure and affects the hemodynamics. The effects of NPV on chronic obstructive pulmonary disease (COPD) patients with pulmonary rehabilitation program remains unknown.

Detailed description

Both of NPV or positive pressure ventilation (PPV) has impact of hemodynamics. NPV with cuirass ventilator increases venous return and leads to ventricular filling and increases cardiac output (CO); In contrast to NPV, the effect of PPV in most situations is a decreased venous return and leads to decreased CO. NPV improving ventilation and work of breathing in patients with chronic obstructive pulmonary disease (COPD).

Conditions

• COPD

Interventions

Type	Name	Description
OTHER	Received negative pressure ventilation	Patients who received a negative pressure during inspiratory phase.

Timeline

• Start date: 2018-01-01
• Primary completion: 2019-11-30
• Completion: 2019-12-31
• First posted: 2019-12-27
• Last updated: 2020-01-18

Locations

1 site across 1 country: Taiwan