Trials / Completed
CompletedNCT04206033
Hemophilia and Bone Metabolism: Study of Monocytic Populations and Inflammatory Proteins
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 73 (actual)
- Sponsor
- Nantes University Hospital · Academic / Other
- Sex
- Male
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The investigators propose, as part of the study, to carry out for each patient: * An analysis of monocytic populations by flow cytometry (CD14, CD16, CD45, CD68, CD115, CCR2, CX3CR1, CD163 and CD206). * A population assessment of Myeloid-Derived Suppressor Cells (MDSC). * Assays of cytokines and chemokines involved in inflammation by multiplex analyzes: Il-1 (α and β), Il-4, Il-6, Il-10, Il-13, TNF- α, TGF- β, CRP , leptin, IFN- β. * Specialized dosages of proteins involved in bone metabolism. RANKL, osteoprotegerin, M-CSF, TRAPCP5.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Observational study | Observational study |
Timeline
- Start date
- 2019-11-29
- Primary completion
- 2020-12-31
- Completion
- 2020-12-31
- First posted
- 2019-12-20
- Last updated
- 2021-07-27
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT04206033. Inclusion in this directory is not an endorsement.