NCT04191408

Predictive Ability of PEEP Induced Changes in CVP to Predict Volume Responsiveness in Mechanically Ventilated Patients After Major Abdominal Surgery

Predictive Ability of PEEP Induced CVP Changes to Predict Volume Responsiveness in Mechanically Ventilated Patients After Major Abdominal Surgery

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: University Hospital Dubrava · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Interventional study which will assess whether an positive end expiratory pressure induced increase of central venous pressure is a valid predictor of volume responsiveness in mechanically ventilated patients after major abdominal surgery assessed by increase of cardiac output after passive leg raise.

Detailed description

Interventional study which will assess whether an positive end expiratory pressure induced increase of central venous pressure is a valid predictor of volume responsiveness in mechanically ventilated patients after major abdominal surgery assessed by increase of cardiac output after passive leg raise.

Conditions

• Surgery
• Critical Illness
• Cardiac Output, Low

Interventions

Type	Name	Description
PROCEDURE	PEEP increase	PEEP increase +5 to +15 cmH2O. PLR at 30 degrees.

Timeline

• Start date: 2019-11-01
• Primary completion: 2020-02-01
• Completion: 2020-02-01
• First posted: 2019-12-09
• Last updated: 2019-12-13

Locations

1 site across 1 country: Croatia