NCT04187924

Effects of SIMEOX on Airway Clearance in Cystic Fibrosis

Effects of the Addition of the SIMEOX Device on Autogenic Drainage in Patients With Cystic Fibrosis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

This study will investigate the contribution of SIMEOX technology on the effectiveness of bronchial drainage. This is a crossover study to evaluate the contribution of SIMEOX on the effectiveness of bronchial drainage (verified by the amount of sputum secretions, the rheology of sputum secretions and the subjective sensation of ease of sputum) in patients with cystic fibrosis. Patients will perform, in randomized order (1) a 30-min session of autogenic drainage, (2) a 30-min session of autogenic drainage with the SIMEOX device. Sputum will be collected during and after the session. The two sessions will be performed with minimum washout time of 24 hours.

Conditions

• Cystic Fibrosis

Interventions

Type	Name	Description
OTHER	Autogenic drainage	Autogenic drainage is an airway clearance technique characterised by breathing control using expiratory airflow to mobilise secretions from smaller to larger airways. The secretions will be collected during the physiotherapy session and during the 24 hours following the session.
DEVICE	SIMEOX + Autogenic drainage	SIMEOX is a device generating a succession of gentle depression at the mouth during the expiratory phase associated with autogenic drainage.

Timeline

• Start date: 2019-11-27
• Primary completion: 2021-11-30
• Completion: 2021-11-30
• First posted: 2019-12-05
• Last updated: 2024-05-08

Locations

1 site across 1 country: Belgium