NCT04184206

Effects of Attention Training Interventions on Depression

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 3 (actual)
• Sponsor: Mclean Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to study the effects of attention training interventions on symptoms and brain function in major depressive disorder.

Detailed description

Attention training programs including mindfulness meditation-based interventions have been shown to be effective for treating depression. Currently the biological and psychological mechanisms of action of attention training for major depression disorder are unknown. The objective of the current study is to improve the investigator's understanding of the mechanisms of attention training interventions for depression. Research participants will include approximately 165 individuals with major depressive disorder randomized to one of three types of attention training programs. Before and after intervention participants will complete a number of biological assessments including MRI, EEG, behavioral tasks, and questionnaires. The study will be completed across three visits: (1) a screening visit; (2) data collection session 1; and (3) data collection session 2.

Conditions

• Depression
• Attention Training
• Symptoms, Cognitive
• Symptoms, Affective
• Symptoms, Behavioral

Interventions

Type	Name	Description
BEHAVIORAL	attention training intervention 1	14-day smartphone-based audio-guided attention training program with heavy mindfulness component
BEHAVIORAL	attention training intervention 2	14-day smartphone-based audio-guided attention training program with moderate mindfulness component
BEHAVIORAL	attention training intervention 3	14-day smartphone-based audio-guided attention training program without mindfulness component

Timeline

• Start date: 2021-08-31
• Primary completion: 2022-04-30
• Completion: 2022-04-30
• First posted: 2019-12-03
• Last updated: 2024-03-19

Locations

1 site across 1 country: United States