NCT04177225

Effect of Diastolic Dysfunction on Dynamic Cardiac Monitors

Evaluation of Dynamic Monitors for the Prediction of Volume Responsiveness in Patients With and Without Diastolic Dysfunction

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 120 (actual)
• Sponsor: University of California, Davis · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This investigator initiated, prospective, observational, single-center study is designed to assess whether dynamic monitors of cardiac function such as stroke volume variation (SVV) that have been shown to predict volume responsiveness differ in clinical utility between patients with and without diastolic dysfunction.

Detailed description

This investigator initiated, prospective, observational, single-center study is designed to assess whether dynamic monitors of cardiac function, such as stroke volume variation (SVV), that have been shown to predict volume responsiveness differ in clinical utility between patients with and without diastolic dysfunction. Specific Aims: * Determine the threshold for the predictive response of SVV with respect to increasing cardiac output for patients with and without diastolic dysfunction. * Compare the trans thoracic ultrasound assessment of left ventricular diastolic function before and after the induction of general anesthesia.

Conditions

• Stroke Volume Variation
• Diastolic Dysfunction

Interventions

Type	Name	Description
PROCEDURE	Trans thoracic Ultrasound Examination	Ultrasound examination of cardiac function before and after induction of general anesthesia.
OTHER	Intravenous fluid administration	Intravenous fluids will be administered as a bolus in response to standard clinical indications

Timeline

• Start date: 2019-02-07
• Primary completion: 2021-02-01
• Completion: 2021-02-01
• First posted: 2019-11-26
• Last updated: 2021-02-12

Locations

1 site across 1 country: United States