Clinical Trials Directory

Trials / Completed

CompletedNCT04165850

Open Label Study to Evaluate Ciprofloxacin/Celecoxib Combination in Patients With ALS

Open Label Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of Ciprofloxacin/Celecoxib Combination in Patients With ALS

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
16 (actual)
Sponsor
NeuroSense Therapeutics Ltd. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This is an open label, off label study, to provide interested ALS patients with Ciprofloxacin/Celecoxib fixed dose combination, while assessing safety and tolerability and routine disease progression measures (ALSFRS-R and Vital Capacity).

Detailed description

Patients will be prescribed a fixed dose combination of Ciprofloxacin and Celecoxib to be taken thrice daily, and will be monitored for safety and tolerability. Additionally, routine disease progression measures will be assessed.

Conditions

Interventions

TypeNameDescription
DRUGFixed dose combination Ciprofloxacin/CelecoxibFixed dose Ciprofloxacin and Celecoxib capsule to be taken thrice daily, total dose 909mg/day

Timeline

Start date
2019-11-25
Primary completion
2021-01-19
Completion
2021-01-19
First posted
2019-11-18
Last updated
2021-03-03

Locations

1 site across 1 country: Israel

Source: ClinicalTrials.gov record NCT04165850. Inclusion in this directory is not an endorsement.